Mycotoxins are regulated in many commodities worldwide and Cannabis is not exempt from mycotoxin contamination. Contamination can occur during storage. It can occur in both indoor and outdoor grows, whether treated or untreated for pesticides. Cannabis can also pull many different contaminants out of the soil it is grown in. Cannabis and its derivative products have remained challenging matrices when analyzing for the regulated mycotoxins, Aflatoxin B1, B2, G1, G2 and Ochratoxin A. Therefore, the main objective of this study was to develop a robust, comprehensive and effective method for the analysis of the regulated mycotoxins in cannabis plant material and derivative products using immunoaffinity columns coupled with LC-MS/MS. The validated method uses an AflaOchra™ immunoaffinity column clean-up procedure that is streamlined for the analysis of cannabis plant material, topicals, tinctures, edibles and concentrates. Immunoaffinity columns were provided by VICAM.™
